Qsymia® is for adults with a BMI* of 30 or more† and should be used with a reduced-calorie diet and increased physical activity for chronic weight management.
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You don’t have to try to lose weight on your own
With Qsymia, lose 4 times more weight than diet and exercise alone‡1
You tried to lose weight by eating less, and it left you feeling hungry all the time. This constantly tested your willpower and left you feeling frustrated, because you never achieved any real weight loss.
Prescription once-daily Qsymia can help you:
24 lbsor more and
keep it off
4 inchesor more off
almost 10%average percent
‡ Qsymia was studied in 2 large trials supporting FDA approval that involved 3754 patients whose BMI was 30 kg/m2 or greater, or 27 kg/m2 or greater with 2 or more weight-related comorbidities such as hypertension, type 2 diabetes mellitus, or dyslipidemia. Presented here are weight loss and waist circumference reduction in the subset of subjects (N = 2076) with a baseline BMI of 30 kg/m2 or greater, and who used study drug for the planned 56 week course of treatment. Patients were randomized to placebo, phentermine 3.75 mg/topiramate 23 mg, phentermine 7.5 mg/topiramate 46 mg, or phentermine 15 mg/topiramate 92 mg. In these trials, it was recommended that patients eat a well-balanced diet and reduce their caloric intake by 500 kcal/day. The precise mechanism of action of the 2 ingredients on chronic weight management is unknown. Your results may vary depending on your BMI, diet, activity, dose of Qsymia, and other factors.1,2
Qsymia helps reduce your hunger and helps you feel full throughout the day
- Works in 2 ways to help you meet your weight loss goals: It reduces your hunger and helps you feel full throughout the day. This helps you minimize snacking and overeating at meals. The precise mechanism of action of the 2 ingredients on chronic weight management is unknown
- Works throughout the day and evening to help you stay on track
- Is FDA approved
Qsymia is a product to help you lose weight. Losing weight can have a positive impact on other conditions, like lowering blood pressure, cholesterol and the risk of Type II Diabetes. Qsymia is not approved for the treatment of these conditions.
Qsymia is a federally controlled substance (CIV) because it contains phentermine and can be abused or lead to drug dependence.
Do not take Qsymia if you are pregnant, planning to become pregnant, or become pregnant during Qsymia treatment; have glaucoma; have thyroid problems (hyperthyroidism); are taking certain medicines called monoamine oxidase inhibitors (MAOIs) or have taken MAOIs in the past 14 days; are allergic to topiramate, sympathomimetic amines such as phentermine, or any of the ingredients in Qsymia. See the end of the Medication Guide for a complete list of ingredients in Qsymia.
Our money-saving offer helps you get started on your path to long-term weight loss
Start your first 2 weeks for FREE
Save up to $95 on your first 30-day prescription
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A comprehensive plan to help you make the most of your commitment to weight loss
Introducing the new Smart Changes™ Program By the makers of Qsymia®
The Smart Changes™ Program combines positive lifestyle changes with a prescription medication proven to help you achieve your goals. It includes:
- The Qsymia “Save Right from the Start” offer
- A free, limited, 3-month subscription to
“The Smart Changes™ Program is designed to help people get the most out of their efforts. FDA-approved Qsymia is proven to reduce hunger and help you feel full, and The Mayo Clinic Diet's clinically-tested techniques can help people focus on the behavioral changes needed to achieve lasting success.”
Dr. Scott Kahan, M.D., M.P.H.
Director of the National Center for Weight and Wellness‡
Restrictions apply. See eligibility conditions on
Smart Changes Program
This limited free-trial offer does not represent an actual or implied endorsement of Qsymia by Mayo Clinic or The Mayo Clinic Diet. Mayo Clinic has authorized VIVUS to distribute The Mayo Clinic Diet. Mayo Clinic does not endorse any non-Mayo products or services.
* BMI (body mass index) measures the amount of fat in the body based on height and weight.
BMI is measured in kg/m2.
† Or a BMI of 27 or more with one weight-related medical condition.
‡ Scott Kahan, MD, MPH, is a paid spokesperson for VIVUS, Inc.
1. Data on File. VIVUS, Inc.
2. Qsymia®(phentermine and topiramate extended-release) capsules CIV [Prescribing Information]. Mountain View, CA: VIVUS, Inc.; 2014.