Qsymia® is for adults with a BMI* of 30 or more and should be used with a reduced-calorie diet and increased physical activity for chronic weight management.

Lose 4 times more weight
than diet and exercise alone‡1 For people with a BMI of 30+, taking the recommended dose of Qsymia.

Prescription once-daily Qsymia can help you:

24 lbs
or more and
keep it off
4 inches
or more off
your waist
almost 10%
average percent
weight loss

Qsymia was studied in 2 large trials supporting FDA approval that involved 3754 patients whose BMI was 30 kg/m2 or greater, or 27 kg/m2 or greater with 2 or more weight-related comorbidities such as hypertension, type 2 diabetes mellitus, or dyslipidemia. Patients were randomized to placebo, phentermine 3.75 mg/topiramate 23 mg, phentermine 7.5 mg/topiramate 46 mg, or phentermine 15 mg/topiramate 92 mg. In these trials, it was recommended that patients eat a well-balanced diet and reduce their caloric intake by 500 kcal/day. Your weight loss may vary depending on your BMI, diet, activity, dose of Qsymia, and other factors.1,2

In a subset analysis, patients with a BMI ≥30 kg/m2 taking the recommended dose of Qsymia (n=2076) lost an average of approximately 10% of their body weight, 24 lbs, and a 4 inch weight reduction after 1 year.1

Start Qsymia for FREE — Continue to save for 36 months.

Our money-savings offer helps you get started on your path to achieving your long-term weight-loss goals.

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You don’t have to try to lose weight on your own
Talk to your doctor about prescription, once-daily Qsymia.

You tried to lose weight by eating less, and it left you feeling hungry all the time. This constantly tested your willpower and left you feeling frustrated, because you never achieved any real weight loss.

Qsymia is an FDA-approved prescription weight-loss medicine that can work with diet and activity to help you lose 20 pounds or more and lose 4 inches or more off your waist. And keep it off!

Qsymia works in 2 ways to help you meet your weight-loss goals

Long term weight loss may be hard. But Qsymia can help on your weight-loss journey. Qsymia’s unique combination of of Phentermine and Topiramate in a once-daily pill can help you:

  • 1Eat less by reducing your appetite
  • 2Feel more satisfied with what you have eaten

Qsymia helps you minimize snacking and overeating at meals and works throughout the day and evening to help you stay on track. The precise mechanism of action of the 2 ingredients on chronic weight management is unknown. Learn more about how Qsymia works.

Our money-saving offer helps you get started on your path to long-term weight loss

Start your first 2 weeks for FREE
Save up to $95 on your first 30-day prescription

Then continue to save each month

Save up to $65 per monthly prescription

Restrictions apply. $95 limit. Pharmacy fees may vary by location.

A comprehensive plan to help you make the most of your commitment to weight loss

Introducing the new Smart Changes™ Program

The Smart Changes™ Program combines positive lifestyle changes with a prescription medication proven to help you achieve your goals. It includes:

  • The Qsymia “Save Right from the Start” offer
  • A free, limited, 3-month subscription to The Mayo Clinic Diet

Learn More

“The Smart Changes™ Program is designed to help people get the most out of their efforts. FDA-approved Qsymia is proven to reduce hunger and help you feel full, and The Mayo Clinic Diet's clinically-tested techniques can help people focus on the behavioral changes needed to achieve lasting success.”

Dr. Scott Kahan, M.D., M.P.H.
Director of the National Center for Weight and Wellness

Get started today!

Restrictions apply. See eligibility conditions on Smart Changes Program page.

This limited free-trial offer does not represent an actual or implied endorsement of Qsymia by Mayo Clinic or The Mayo Clinic Diet. Mayo Clinic has authorized VIVUS to distribute The Mayo Clinic Diet. Mayo Clinic does not endorse any non-Mayo products or services.

* BMI (body mass index) measures the amount of fat in the body based on height and weight. BMI is measured in kg/m2.
Or a BMI of 27 or more with one weight-related medical condition.
Scott Kahan, MD, MPH, is a paid spokesperson for VIVUS, Inc.

1. Data on File. VIVUS, Inc.
2. Qsymia®(phentermine and topiramate extended-release) capsules CIV [Prescribing Information]. Mountain View, CA: VIVUS, Inc.; 2014.